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The comparison results of anti-cancer effect between clinically used combinations and Ⅲ12 on MCF-7 cell line.
| Predicted ranking | Group number | The IC50 (nM) of drug combinations | The best IC50 | |||
|---|---|---|---|---|---|---|
| Ⅰ | Ⅱ | Ⅲ | Ⅳ | |||
| 1 | Ⅲ12 | 90.43 | 31.37 | 30.88 | 42.94 | 30.88 |
| 60 | Ⅱ3 | 570.00 | 440.00 | 377.18 | — | 377.18 |
| 92 | Ⅲ55 | 3695.00 | 7789.00 | 9444.00 | 814.10 | 814.10 |
Note: the predicted ranking included 120 drug combinations and individual drugs themselves.
