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The anti-cancer effect of Ⅲ12 and Ⅳ33 on MCF-7, MDA-MB-231 and MDA-MB-468 cells.
| Group number | Cell line | The IC50 (nM) of drug combinations | The best IC50 | ||||
|---|---|---|---|---|---|---|---|
| Ⅰ | Ⅱ | Ⅲ | Ⅳ | Ⅴ | |||
| Ⅲ12 | MCF-7 | 90.4 | 31.3 | 30.8 | 42.9 | — | 30.8 |
| MDA-MB-468 | 137.8 | 115.5 | 410.5 | 468.5 | — | 115.5 | |
| MDA-MB-231 | 15,720 | 8044.0 | 887.0 | 4666.0 | — | 887.0 | |
| Ⅳ33 | MCF-7 | 8090.0 | 787.6 | 4355.0 | 788.9 | 1296.0 | 787.6 |
| MDA-MB-468 | 2803.0 | 1275.0 | 1988.0 | 1451.0 | 2665.0 | 1275.0 | |
| MDA-MB-231 | 177.5 | 52.3 | 139.8 | 2152.0 | 167.5 | 52.3 | |
