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. 2022 Dec 15;9:1068157. doi: 10.3389/fmed.2022.1068157

TABLE 2.

Summary of pooled odds ratios of variables associated with significant liver fibrosis.

Variables Pooled OR (95% CI) I 2 References Number of patients
Age 2.20 (1.42–3.40) 0% (31, 38, 44, 45) 344
Male 1.10 (0.87–1.39) 3.2% (27, 29, 31, 35, 36, 38, 39, 41, 42, 4446) 1,851
PASI > 10 1.67 (0.94–2.95) 37% (27, 31, 41, 46) 500
Psoriatic arthritis 1.30 (0.82–2.06) 30.6% (27, 35, 36, 46) 738
Cumulative MTX dose >1500 mg 1.58 (0.91–2.75) 0% (29, 39, 45, 46) 422
BMI > 30 3.67 (2.37–5.68) 48.8% (27, 31, 36, 41, 44) 602
Diabetes mellitus 6.23 (4.39–8.84) 42.4% (27, 31, 35, 36, 41, 4446) 1,200
Hypertension 2.82 (1.68–4.74) 0% (27, 41, 45, 46) 409
Dyslipidemia 3.08 (1.90–4.98) 0% (27, 31, 41, 45, 46) 541
Metabolic syndrome 5.98 (3.63–9.83) 17% (35, 39, 41, 45, 46) 768

BMI, body mass index; MTX, methotrexate; OR, odds ratio; PASI, psoriasis area severity index.