TABLE 4.
Logistic regression models on the FIB-4 cut-off of >2.67 (fibrosis/no fibrosis) and regressors.
| Raw model |
Adjusted model |
|||||||
| OR | CI 95% | SE | P-value | OR | CI 95% | SE | P-value | |
| Whole retina SVD | 0.94 | 0.90–0.98 | 0.02 | <0.01 | 0.99 | 0.94–1.05 | 0.02 | 0.85 |
| Age (years) | 1.19 | 1.10–1.16 | 0.02 | <0.01 | ||||
| Sex (female) | 0.73 | 0.46–1.18 | 0.24 | 0.20 | ||||
| Education (years) | 0.98 | 0.92–1.05 | 0.03 | 0.69 | ||||
| Hypertension (yes) | 0.89 | 0.48–1.68 | 0.32 | 0.73 | ||||
| Diabetes (yes) | 0.74 | 0.34–1.63 | 0.40 | 0.62 | ||||
| Alcohol consumption | 1.78 | 0.66–4.80 | 0.50 | 0.25 | ||||
| Triglycerides (mg/dl) | 1.01 | 0.99–1.01 | 0.02 | 0.94 | ||||
| Cholesterol (mg/dl) | 0.98 | 0.98–0.99 | 0.03 | <0.01 | ||||
| Whole retina DVD | 0.94 | 0.91–0.97 | 0.01 | <0.01 | 1.01 | 0.96–1.06 | 0.02 | 0.85 |
| Age (years) | 1.12 | 1.10–1.17 | 0.02 | <0.01 | ||||
| Sex (female) | 0.72 | 0.45–1.17 | 0.24 | 0.20 | ||||
| Education (years) | 0.98 | 0.92–1.05 | 0.03 | 0.69 | ||||
| Hypertension (yes) | 0.88 | 0.47–1.66 | 0.32 | 0.73 | ||||
| Diabetes (yes) | 0.75 | 0.34–1.65 | 0.40 | 0.62 | ||||
| Alcohol consumption | 1.76 | 0.66–4.75 | 0.50 | 0.25 | ||||
| Triglycerides (mg/dl) | 0.99 | 0.99–1.01 | 0.01 | 0.94 | ||||
| Cholesterol (mg/dl) | 0.9 8 | 0.98–0.99 | 0.01 | <0.01 | ||||
| GCC total Th | 0.98 | 0.96–0.99 | 0.01 | 0.02 | 0.98 | 0.97–0.99 | 0.01 | 0.04 |
| Age (years) | 1.11 | 1.11–1.16 | 0.02 | <0.01 | ||||
| Sex (female) | 0.72 | 0.45–1.18 | 0.24 | 0.19 | ||||
| Education (years) | 0.98 | 0.91–1.05 | 0.03 | 0.61 | ||||
| Hypertension (yes) | 0.80 | 0.43–1.52 | 0.32 | 0.51 | ||||
| Diabetes (yes) | 0.71 | 0.32–1.58 | 0.40 | 0.57 | ||||
| Alcohol consumption | 1.72 | 0.64–4.67 | 0.50 | 0.28 | ||||
| Triglycerides (mg/dl) | 1.01 | 0.98–1.01 | 0.02 | 0.95 | ||||
| Cholesterol (mg/dl) | 0.98 | 0.97–0.99 | 0.03 | <0.01 | ||||
| ONH RNFL Th | 0.99 | 0.97–1.01 | 0.01 | 0.26 | 0.98 | 0.97–1.01 | 0.01 | 0.34 |
| Age (years) | 1.11 | 1.10–1.16 | 0.02 | <0.01 | ||||
| Sex (female) | 0.73 | 0.46–1.19 | 0.24 | 0.21 | ||||
| Education (years) | 0.98 | 0.92–1.05 | 0.03 | 0.68 | ||||
| Hypertension (yes) | 0.86 | 0.46–1.63 | 0.32 | 0.66 | ||||
| Diabetes (yes) | 0.73 | 0.33–1.61 | 0.40 | 0.60 | ||||
| Alcohol consumption | 1.77 | 0.66–4.77 | 0.50 | 0.26 | ||||
| Triglycerides (mg/dl) | 1.01 | 1.01–1.01 | 0.01 | 0.98 | ||||
| Cholesterol (mg/dl) | 0.99 | 0.98–0.99 | 0.01 | <0.01 | ||||
Statistically significant data are indicated in bold type. OR, odds ratio; CI, confidence interval; SE, standard error; Th, thickness; SVD, superficial vessel density; DVD, deep vessel density; GCC, ganglion cell complex; ONH, optic nerve head; RNFL, retinal nerve fiber layer.