Skip to main content
. 2022 Dec 20;8(12):e12472. doi: 10.1016/j.heliyon.2022.e12472

Table 2.

Comparison of MIC values between free EOs and their active components against different types of microbial contaminations.

Microorganism Whole EO
EO Active Components
References
Type MICa Type MIC
Gram-positive bacteria
S. aureus Oregano 0.06–0.12%b Carvacrol
Thymol
0.01–0.03%
0.03–0.06%
Nostro et al. (2007)
Oregano 5 μl/ml Carvacrol 2.5 μl/ml dos Santos Rodrigues et al. (2017)
Oregano 575 mg/l Carvacrol
Thymol
175 mg/l
140 mg/l
Lambert et al. (2001)
Lemongrass 0.54 μl/ml Citral
Geraniol
Myrcene
0.62–1.25 μl/mlc
0.62–1.25 μl/ml
>17.5 μl/ml
Aiemsaard et al. (2011)
S. aureus (Biofilms) Oregano 0.25–0.50% Carvacrol
Thymol
0.03–0.12%
0.06–0.12%
Nostro et al. (2007)
Oregano 10 μl/ml Carvacrol 5 μl/ml dos Santos Rodrigues et al. (2017)
S. epidermidis Oregano 0.06–0.12% Carvacrol
Thymol
0.01–0.03%
0.03–0.06%
Nostro et al. (2007)
S. epidermidis (Biofilms) Oregano 0.12–0.50% Carvacrol
Thymol
0.03–0.12%
0.03–0.12%
Nostro et al. (2007)
L. monocytogenes Oregano
Thyme
0.05%
0.05%
Carvacrol 0.05% Desai et al. (2012)
Streptococcus agalactiae Lemongrass 0.27–0.54 μl/ml Citral
Geraniol
Myrcene
0.31–0.62 μl/ml
0.31 μl/ml
>17.5 μl/ml
Aiemsaard et al. (2011)
Gram-negative bacteria
E. coli Thyme 1.60 mg/ml Carvacrol
Thymol
0.20 mg/ml
0.20 mg/ml
Vidács et al., (2018)
Cinnamon 0.40 mg/ml CINd 0.20 mg/ml
Cinnamon 250 μg/ml CINd 500 μg/ml Chang et al. (2001)
Lemongrass 0.54–1.09 μl/ml Citral
Geraniol
Myrcene
1.25–2.5 μl/ml
1.25–2.5 μl/ml
>17.5 μl/ml
Aiemsaard et al. (2011)
S. Typhimurium Oregano
Thyme
0.05–0.10%
0.05–0.10%
Carvacrol 0.02% Soni et al. (2013)
P. aeruginosa Oregano 1648 mg/l Carvacrol
Thymol
450 mg/l
385 mg/l
Lambert et al. (2001)
Cinnamon 250 μg/ml CINd 1000 μg/ml Chang et al. (2001)
K. pneumoniae Cinnamon 500 μg/ml CINd 1000 μg/ml Chang et al. (2001)
B. cereus Lemongrass 0.13 μl/ml Citral
Geraniol
Myrcene
0.15 μl/ml
0.31 μl/ml
>17.5 μl/ml
Aiemsaard et al. (2011)
Fungi
C. albicans C. nardus 64 μg/ml Citronellal 512 μg/ml Trindade et al. (2015)
a

MIC: Minimum Inhibitory Concentration.

b

MIC values were determined in a range as they were tested on several strains.

c

MIC values were determined in a range as the experiments were done in triplicates.

d

CIN: Cinnamaldehyde.