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. 2022 Dec 14;5(1):fcac327. doi: 10.1093/braincomms/fcac327

Table 3.

Results of multiple regression with robust estimation of standard errors for connectivity disruption predictors of each deficit measure

Complexity Lexical syntax Phonology Semantics
Tracts
  Volume −0.0063 (−0.0095, −0.0032)** −0.0066 (−0.011, −0.002)** 0.00021 (−0.0032, 0.0036) −0.0048 (−0.0085, −0.0011)*
 Arcuate fasciculus 0.008 (−0.0021, 0.018) −0.0068 (−0.014, 0.00049). 0.0097 (−0.0027, 0.022) 0.00068 (−0.0069, 0.0083)
 Frontal aslant tract −0.0017 (−0.0091, 0.0056) −0.0014 (−0.0078, 0.005) 0.0012 (−0.0069, 0.0093) −0.0054 (−0.014, 0.0036)
 Superior longitudinal −0.0081 (−0.019, 0.003) 0.00041 (−0.0099, 0.011) −0.0095 (−0.022, 0.0033) 0.01 (−0.0015, 0.022).
 Uncinate fasciculus 0.0044 (−0.0056, 0.014) 0.0025 (−0.0093, 0.014) −0.005 (−0.017, 0.0068) 0.0053 (−0.0064, 0.017)
 Inferior fronto-occipital 0.000039 (−0.008, 0.0081) 0.0047 (−0.0031, 0.012) −0.0029 (−0.013, 0.0072) −0.0057 (−0.015, 0.0038)
Whole-brain network
 Volume −0.0072 (−0.011, −0.0037)** −0.0089 (−0.014, −0.0034)** 0.00011 (−0.0042, 0.0044) −0.0062 (−0.01, −0.002)**
 Global efficiency −13 (−200, 170) −150 (−380, 81) 130 (−82, 350) −61 (−270, 150)
 Ave clustering coefficient 150 (−390, 700) 340 (−300, 980) −340 (−940, 260) 490 (−46, 1000).
 Characteristic path length 0.00070 (−0.0013, 0.0027) −0.0012 (−0.0035, 0.0012) 0.00022 (−0.0022, 0.0027) 0.0029 (0.00051, 0.0054)*
Language network
 Volume −0.0072 (−0.0097, −0.0046)** −0.0078 (−0.011, −0.0045)** −0.00011 (−0.0026, 0.0024) −0.0025 (−0.0059, 0.00096)
 Global efficiency 1.4 (0.084, 2.8)* 2.8 (1.6, 4)** −2.1 (−3.2, −0.91)** −2 (−3.3, −0.65)**
 Ave clustering coefficient −2.1 (−13, 8.8) 8.8 (−0.5, 18) . −8.1 (−16, −0.54)* 9 (1.2, 17)*
 Characteristic path length −0.00011 (−0.0015, 0.0013) 0.00028 (−0.00084, 0.0014) −0.0012 (−0.0023, −9.8e-05)* −0.00019 (−0.0011, 0.00077)

Note: Values show the regression coefficient estimate (95% confidence interval in brackets).

** P < 0.01, * P < 0.05, P < 0.1.