Table 1.
Characteristics of the study population, stratified by cancer type
| Cancer Type | ||||
|---|---|---|---|---|
| Breast n = 7,680 |
Colorectal n = 5,462 |
Lung n = 8,817 |
Prostate n = 7,181 |
|
| Age, n (%) | ||||
| 66 – 69 | 1,996 (26.0) | 1,112 (20.4) | 2,082 (23.6) | 2,637 (36.7) |
| 70 – 74 | 1,994 (26.0) | 1,211 (22.2) | 2,568 (29.1) | 2,262 (31.5) |
| 75 – 79 | 1,548 (20.2) | 1,101 (20.2) | 1,964 (22.3) | 1,320 (18.4) |
| 80+ | 2,142 (27.9) | 2,038 (37.3) | 2,203 (25.0) | 962 (13.4) |
| Sex, n (%) | ||||
| Male | - | 2,658 (48.7) | 4,598 (52.2) | - |
| Female | - | 2,804 (51.3) | 4,219 (47.9) | - |
| Race/Ethnicity, n (%) | ||||
| Non-Hispanic White | 6,983 (90.9) | 5,007 (91.7) | 8,048 (91.3) | 6,103 (85.0) |
| Non-Hispanic Black | 621 (8.1) | 357 (6.5) | 689 (7.8) | 739 (10.3) |
| All Other | 76 (1.0) | 98 (1.8) | 80 (0.9) | 339 (4.7) |
| Stage, n (%) | ||||
| Local | 5,300 (69.0) | 2,051 (37.6) | 2,324 (26.4) | 5,087 (70.8) |
| Regional | 1,804 (23.5) | 2,101 (38.5) | 2,334 (26.5) | 893 (12.4) |
| Distant | 447 (5.8) | 928 (17.0) | 3,803 (43.1) | 557 (7.8) |
| Unstaged/Unknown | 129 (1.7) | 382 (7.0) | 356 (4.0) | 644 (9.0) |
| Died, n (%) | 1,068 (13.9) | 1,692 (31.0) | 5,470 (62.0) | 754 (10.5) |
| Follow-up time in months, median (IQR) | 23 (12 – 36) | 18 (8 – 32) | 10 (4 – 20) | 23 (12 – 37) |
| Elixhauser Comorbidity Count, n (%) | ||||
| Mean (Std. Dev) | 2.56 (2.59) | 2.72 (2.92) | 2.99 (2.91) | 1.83 (2.17) |
| Median (IQR) | 2 (0 – 4) | 2 (0 – 4) | 2 (0 – 5) | 1 (0 – 3) |
| 0 | 2,006 (26.1) | 1,585 (29.0) | 2,246 (25.5) | 2,643 (36.8) |
| 1 or 2 | 2,461 (32.0) | 1,560 (28.6) | 2,321 (26.3) | 2,486 (34.6) |
| 3 or 4 | 1,765 (23.0) | 1,137 (20.8) | 2,011 (22.8) | 1,276 (17.8) |
| 5+ | 1,448 (18.9) | 1,180 (21.6) | 2,239 (25.4) | 776 (10.8) |
| Claims Frailty Index, n (%) | ||||
| Mean (Std. Dev) | 0.15 (0.06) | 0.16 (0.06) | 0.16 (0.07) | 0.13 (0.05) |
| Median (IQR) | 0.14 (0.10 – 0.18) | 0.14 (0.10 – 0.18) | 0.15 (0.10 – 0.20) | 0.12 (0.10 – 0.15) |
| Non-Frail | 483 (6.3) | 296 (5.4) | 359 (4.1) | 909 (12.7) |
| Pre-Frail | 5,843 (76.1) | 4,109 (75.2) | 6,339 (71.9) | 5,657 (78.8) |
| Mildly Frail | 1,093 (14.2) | 825 (15.1) | 1,689 (19.2) | 532 (7.4) |
| Moderately/Severely Frail | 261 (3.4) | 232 (4.3) | 430 (4.9) | 83 (1.2) |
| Multimorbidity Weighted Index | n = 5,121 | n = 3,528 | n = 5,741 | n = 4,357 |
| Mean (Std. Dev) | 7.36 (6.2) | 8.20 (6.88) | 10.19 (7.73) | 6.19 (5.67) |
| Median (IQR) | 5.86 (2.63 – 10.27) | 6.38 (2.96 – 11.81) | 8.52 (4.32 – 14.62) | 4.92 (1.62 – 8.81) |