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. 2022 Dec 29;14:146. doi: 10.1186/s13073-022-01151-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Sensitivity of Omicron subvariants to therapeutic bebtelovimab. a Neutralization curves against D614G, Delta, and Omicron subvariants are shown for bebtelovimab. Data are the mean ± s.d. of 2 independent experiments, each with an intra-assay duplicate. b Fifty percent and 90% inhibition concentration (IC₅₀ and IC₉₀) values against D614G, Delta, and Omicron subvariants are shown for bebtelovimab. IC₅₀ and IC₉₀ values were calculated from two independent experiments. c Fold change of IC₅₀ and IC₉₀ of the antibody against Delta and each Omicron subvariant compared to D614G. The horizontal dotted lines represent IC₅₀ and IC₉₀