. Author manuscript; available in PMC: 2022 Dec 29.

Published in final edited form as: DNA Repair (Amst). 2022 Sep 9;119:103402. doi: 10.1016/j.dnarep.2022.103402

Table 1.

G4 Motif Sequences and Characterization

G4 Motif Sequence^a	ID^b	Length (nts)	Location^c	Topology^d	Tm (°C)	Quadron Score
5’ GGGcgaaGGGGcgagccaGGGGtaaGGGG 3’	FER1L4	29	intron	antiparallel	75.6	9.19
5’GGGGcGGGccGGGGGcGGGGtcccggcGGGG3’	VEGF	31	promoter	parallel	83.5	26.09
5’ GGGGcGGGccGGGGGcGGGG 3’	VEGF^mut	20	n.a.	parallel	85.5	24.19
5’ GGGGcggacccGGGGcGGGGcaaGGG 3’	TAGLN2	26	enhancer	hybrid	68	13.46

G-tracts, underlined; loops, lowercase

ID of G4 based on gene in which it is located or near

Based on human genome (Dec. 2013 Human GRCh38/hg38)

Determined by circular dichroism

nts, nucleotides; Tm, thermal melting temperature; n.a., not applicable