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DIO-induced bone loss in rats. (A) Representative Micro-CT 3D reconstructions of the two groups. (B–E) Trabecular bone parameters at the distal femoral metaphysis after 10 weeks, including BMD, BV/TV, Tb.N, and Tb.Th. (F, G) Cortex bone parameters at the middle femur after 10 weeks, including Ct.Th and Ct.V. Data are expressed as the mean ± SEM. n = 6, *P < 0.05, **P < 0.01, ns, no significance.
