. Author manuscript; available in PMC: 2023 Jan 1.

Published in final edited form as: Curr Probl Surg. 2021 Jul 7;59(1):101030. doi: 10.1016/j.cpsurg.2021.101030

Table 3.

Rule of two’s and three’s for familial melanoma.

• Any patient with three primary melanomas

• A patient with one primary melanoma and two 1^st or 2^nd degree relatives (same side) with a diagnosis of melanoma or pancreatic cancer