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Dose-dependent inhibition of cell detachment by brefeldin A
| Brefeldin A concn (μM) | Morphologic effectsa |
|---|---|
| 0 | 3.6 ± 0.48 |
| 7.5 | 2.4 ± 0.48 |
| 15 | 1.4 ± 0.48 |
| 30 | 0.2 ± 0.4 |
| 60 | 0 |
The morphologic changes of HEp-2 cells produced by Pet are shown as means ± SD standard deviation (n = 5 wells) from previously reported scores (see Materials and Methods section): 1, elongated cells; 2, rounded cells; 3, 50% detachment of the cells; 4, 95% detachment of cells.
