ANK3 as a gene expression biomarker for biological age. ANK3 gene expression in whole blood. (a) In live psychiatric patients. (b) In individuals who committed suicide. (c) Results by gender and diagnosis. ANK3 expression levels are Z-scored by gender and diagnosis for the live psychiatric participants cohort, and Z-scored by gender for the coroner suicide cohort. Bold values are nominally significant. Italic values trend to significance. AUC, areas under the curve, for younger age vs middle age; BP, bipolar; MDD, major depressive disorder; mood NOS, mood disorder not otherwise specified; psychosis NOS, psychotic disorder not otherwise specified; OR, odds ratio; PTSD, posttraumatic stress disorder; ROC, receiver operating characteristic.