Fig. 3.

A in vitro cytotoxicity of ac-LK on MSCs. B Cellular uptake activity of Tamra-LK on MSCs at 50 nM and 300 nM. C Cellular uptake activities of FAM-miRNA 2861 only, complexes (50 nM of FAM-miRNA 2861 with 1, 3 and 6 equivalent of ac-LK) using flow cytometry, D Representative Confocal laser scanning electron microscopic images of cell treated with FAM-miRNA 2861 only (50 nM) and Complexes (50 nM of FAM-miRNA 2861 with 1, 3, 6 and 12 equivalent ac-LK). The complex of FAM-miRNA 2861 and Lipofectamine was used as a positive control. Fluorescence ( +) cells means the relative fluorescence intensity of FAM-miRNA 2861 based on control cells with no fluorescence