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. 2022 Dec 29;29(5):642–650. doi: 10.1016/j.cmi.2022.12.020

Table 4.

Factors associated with negative outcomes, with a multivariate logistic regression (best model according to Akaike Information Criteria (AIC))


Death on day 28
ICU
Need for oxygen
Best model p Best model p Best model p
Age 1.06 [1.04-1.08] <0.001 1.03 [1.02-1.03] <0.001
Sex: male 1.25 [0.82-1.90] 0.304 1.37 [1.02-1.83] 0.036
Diabetes 1.51 [0.95-2.36] 0.076
Kidney failure 2.52 [1.44-4.31] 0.001 2.30 [1.29-3.97] 0.004
Previous SARS-CoV-2 infection 0.29 [0.02-1.59] 0.247 0.36 [0.02-1.81] 0.325
Vaccination 0.50 [0.32-0.77] 0.002 0.40 [0.26-0.62] <0.001 0.34 [0.25-0.46] <0.001
Pulmonary diseases 1.51 [0.86-2.56] 0.138 1.68 [0.96-2.85] 0.060 1.91 [1.19-3.12] 0.009
O2 at home 8.41 [1.58-156.23] 0.044
Solid cancer for <3 mo 7.99 [2.97-20.80] <0.001
Haematological cancer 3.84 [1.67-8.29] 0.001
Immunosuppressed 1.58 [1.03-2.46] 0.038

Models were explored with a full model including the variable ‘gender’, ‘Age’, ‘Diabetes’, ‘Hypertension (HTA)’, ‘KidneyFailure’, ‘O2_home’, ‘CardiacFailure’, ‘ImmunoSup’, ‘previousSARS-CoV-2 infection’, ‘Vaccination’, ‘PulmDis’, ‘SolidCancer3M’, ‘HematoK’, and ‘OneComorb’. ‘Tobacco’, ‘BMI’, and ‘overweight’ were not included owing to more than 50% of missing data. No interactions were found. ICU, intensive care unit.