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. 2022 Dec 19;11(24):e027627. doi: 10.1161/JAHA.122.027627

Figure 2. Associations of Dietary Exposure to Nitrites and Nitrates With Cardiovascular and Hypertension Risks, NutriNet‐Santé Cohort, France, 2009 to 2021 (n=106 288).

Figure 2

For total nitrite and nitrate intakes and from natural sources, sex‐specific tertiles of consumption were defined. Cutoffs were: 4.09 mg/d and 5.59 mg/d in women, and 5.21 mg/d and 7.52 mg/d in men for total nitrites; 152.3 mg/d and 233.4 mg/d in women, and 162.2 mg/d and 251 mg/d in men for total nitrates; 3.88 mg/d and 5.37 mg/d in women, and 4.94 mg/d and 7.10 mg/d in men for nitrites from natural sources; 152.2 mg/d and 233.2 mg/d in women, and 161.9 mg/d and 250.7 mg/d in men for nitrates from natural sources. For nitrites and nitrates from food additives, 3 categories of consumption were defined: nonconsumers, low consumers, and high consumers (separated by sex‐specific median among consumers). Cutoffs were: 0.19 mg/d in women and 0.25 mg/d in men for nitrites from food additives; 0.36 mg/d in women and 0.46 mg/d in men for nitrates from food additives; 2.23 mg/d in women and 2.23 mg/d in men for potassium nitrite (e249); 0.19 mg/d in women and 0.25 mg/d in men for sodium nitrite (e250); 0.04 mg/d in women and 0.05 mg/d in men for sodium nitrate (e251); and 0.36 mg/d in women and 0.46 mg/d in men for potassium nitrate (e252). HR indicates hazard ratio; and Ref, reference category.