Table 1.
Characteristics of Framingham Heart Study Offspring Cohort Sample (N=1502)
| Clinical characteristics | |
|---|---|
| Age, y | 67±9 |
| Women | 811 (54) |
| Height, meters | 1.68±0.1 |
| Weight, kg | 78.5±16.8 |
| Systolic blood pressure, mm Hg | 128±17 |
| Diastolic blood pressure, mm Hg | 74±10 |
| Heart rate, beats/min | 62±10 |
| Total:HDL cholesterol ratio | 3.5±1.0 |
| Use of antihypertensive medications | 758 (51) |
| Use of lipid‐lowering medications | 710 (47) |
| Diabetes | 190 (13) |
| Smoking | 118 (8) |
| Prevalent cardiovascular disease | 69 (5) |
| CMR measures | |
| Aortic arch pulse wave velocity, m/s | 9±5 |
| Aortic strain, % | 17±9 |
| LV end‐diastolic volume index, mL/m2 | 66±12 |
| LV end‐systolic volume index, mL/m2 | 22±8 |
| LV mass index, g/m2 | 55±12 |
| LV ejection fraction, % | 67±7 |
| Echocardiography measures | |
| E wave deceleration time, ms | 219±33 |
| E' wave area, cm2 | 0.9±0.3 |
| Transmitral E/A ratio | 0.9±0.3 |
| Mitral annular e' (lateral), cm/s | 10±2 |
| E/e' | 7±2 |
Data are reported as number (percentage) for categorical variables and mean (SD) for continuous variables. Prevalent cardiovascular disease as adjudicated by the Framingham Heart Study includes history of stroke, transient ischemic attack, and coronary heart disease. Coronary heart disease is defined as myocardial infarction (diagnostic ECG, cardiac biomarkers, and clinical presentation), coronary insufficiency (unstable angina), or stable angina. CMR indicates cardiac magnetic resonance; HDL, high‐density lipoprotein; and LV, left ventricular.