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. Author manuscript; available in PMC: 2022 Dec 29.
Published in final edited form as: Int J Infect Dis. 2022 Oct 22;125:265–274. doi: 10.1016/j.ijid.2022.10.027

Table 3.

Clinical presentations of newly registered cases of leprosy in Japan, 1993–2020.

Mainland
Okinawa
Nonautochthonous
Total
1993–2000 2001–2010 2011–2020 1993–2000 2001–2010 2011–2020 1993–2000 2001–2010 2011–2020 1993–2020

Number of cases 21 11 2 35 11 5 76 65 34 260
Sex Male 10 6 2 22 8 2 56 51 21 178
Female 11 5 0 13 3 3 20 14 13 82
Male/female ratio 0.9 1.2 0.0 1.7 2.7 0.7 2.8 3.6 1.6 2.2
Age Median age (IQR 25%–75%) 77 (69–80) 73 (47–80) 76 (75–76) 61 (46–73.5) 64 (46.5–70.5) 81 (74–83) 32 (25.8–39.3) 31 (25–37) 33 (27–45) 36 (28–59.3)
Children younger than 15 years 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (1.3%) 0 (0%) 0 (0%) 1 (0.4%)
Ridley-Jopling classification I 0 (0%) 1 (9.1%) 0 (0%) 2 (5.7%) 0 (0%) 0 (0%) 2 (2.6%) 2 (3.1%) 0 (0%) 7 (2.7%)
TT 1 (4.8%) 0 (0%) 0 (0%) 4 (11.4%) 2 (18.2%) 0 (0%) 13 (17.1%) 2 (3.1%) 2 (5.9%) 24 (9.2%)
BT 5 (23.8%) 1 (9.1%) 1 (50%) 15 (42.9%) 5 (45.5%) 1 (20.0%) 23 (30.3%) 16 (24.6%) 12 (35.3%) 79 (30.4%)
BB 0 (0%) 1 (9.1%) 0 (0%) 5 (14.3%) 0 (0%) 0 (0%) 9 (11.8%) 3 (4.6%) 1 (2.9%) 19 (7.3%)
BL 11 (52.4%) 4 (36.4%) 1 (50%) 4 (11.4%) 4 (36.4%) 3 (60.0%) 15 (19.7%) 26 (40.0%) 8 (23.5%) 76 (29.2%)
LL 3 (14.3%) 4 (36.4%) 0 (0%) 5 (14.3%) 0 (0%) 1 (20.0%) 14 (18.4%) 16 (24.6%) 10 (29.4%) 53 (20.4%)
PNL 1 (4.8%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (2.9%) 2 (0.8%)
WHO classification Multibacillary 16 (76.2%) 10 (90.9%) 2 (100%) 21 (60.0%) 5 (45.5%) 4 (80.0%) 44 (57.9%) 53 (81.5%) 21 (61.8%) 176 (67.7%)
Paucibacillary 5 (23.8%) 1 (9.1%) 0 (0%) 14 (40.0%) 6 (54.5%) 1 (20.0%) 32 (42.1%) 12 (18.5%) 13 (38.2%) 84 (32.3%)
G2D (+) NA 4 (36.4%) 2 (100%) NA 1 (9.1%) 0 (0%) NA 6 (9.2%) 6 (17.6%) 19 (7.3%)
Duration between onset and the first consultation ≤1 year 6 (28.6%) 7 (63.6%) 1 (50.0%) 10 (28.6%) 5 (45.5%) 4 (80.0%) 20 (26.3%) 48 (73.8%) 20 (58.8%) 121 (46.5%)
1–2 years 4 (19.0%) 0 (0%) 0 (0%) 9 (25.7%) 1 (9.1%) 0 (0%) 14 (18.4%) 1 (1.5%) 0 (0%) 29 (11.2%)
2–4 years 2 (9.5%) 1 (9.1%) 0 (0%) 5 (14.3%) 2 (18.2%) 1 (20.0%) 17 (22.4%) 12 (18.5%) 6 (17.6%) 46 (17.7%)
5–9 years 1 (4.8%) 2 (18.2%) 1 (50.0%) 3 (8.6%) 2 (18.2%) 0 (0%) 4 (5.3%) 2 (3.1%) 3 (8.8%) 18 (6.9%)
≥10 years 5 (23.8%) 1 (9.1%) 0 (0%) 4 (11.4%) 1 (9.1%) 0 (0%) 5 (6.6%) 2 (3.1%) 4 (11.8%) 22 (8.5%)
No data 3 (14.3%) 0 (0%) 0 (0%) 4 (11.4%) 0 (0%) 0 (0%) 16 (21.1%) 0 (0%) 1 (2.9%) 24 (9.2%)
Family history of leprosy (+) 1 (4.8%) 1 (9.1%) 0 (0%) 4 (11.4%) 2 (18.2%) 1 (33.3%) 9 (15.8%) 12 (20.7%) 2 (6.9%) 32 (12.3%)
No data 5 (23.8%) 1 (9.1%) 1 (50.0%) 19 (54.3%) 5 (45.5%) 2 (40.0%) 19 (25.0%) 7 (10.8%) 5 (14.7%) 64 (24.6%)

I, indeterminate; TT, tuberculoid; BT, borderline tuberculoid; BB, borderline borderline; BL, borderline lepromatous; LL; lepromatous; PNL, pure neuritic leprosy; WHO, World Helath Organization; G2D, grade-II disabilities.