Table 2.

Recent advancements on nanozymes employed for different applications in biomedicine

Nanozyme	Enzyme activity	Application	Main findings	Reference
Two-dimensional vanadium carbide Mxene nanoenzyme	SOD, CAT, POD, GPx, TPx, and HPO	Therapeutic effects on inflammatory and neurodegenerative diseases	Cytoprotection against oxidative stress and high biocompatibility	[9]
Selenium-polydopamine nanozyme	SOD and CAT	Therapy in Alzheimer's disease	Significant antioxidant activity, neuroprotection effects, and enhance cognitive ability	[90]
Platinum loaded CoSn(OH)6 nanocubes	POD	Detection of dopamine	Appreciable thermostability, excellent stability and sensitive colorimetric platform	[91]
Melanin-like nanoparticles	Oxidase	Therapeutic effects	Nanocarriers, antioxidant activity, and potential therapy option for COVID-19	[92]
Chitosan-Modified Fe3O4 Nanozymes	POD, CAT, and SOD	Antibacterial effect	Stimulated the production of ROS in drug-sensitive and drug-resistant bacteria	[93]
Carbon dots confined in N-doped carbon	POD	Detection of cancer	Potential non-invasively clinical diagnosis and early-stage detection	[94]
Bimetallic phosphide nanoparticle	POD and GPX	Cancer therapy	Activate the immune response, good biocompatibility, and significant oxidative damage of the cancer cells	[95]

SOD Superoxide dismutase, CAT catalase, POD peroxidase, GPx glutathione peroxidase, TPx thiol peroxidase, HPO haloperoxidase, ROS reactive oxygen species