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. 2022 Nov 4;9(36):2204077. doi: 10.1002/advs.202204077

Table 3.

Modelling of iron load and deferasirox doses and costs based on List et al.[ 45 ]

Mean transfusion rate: 4.1 pRBC units per month over 12 months (Σ = 49 pRBCs per year)

Required amount of Deferasirox 20 mg kg−1 bw/d

Mean net excretion = 0.329 mg Fe/kg bw/d

Required amount of Deferasirox 40 mg kg−1 bw/d

Mean net excretion = 0.445 mg Fe/kg bw/d

Minimum iron content per pRBC unit (133.42 mg) 17.91 mg Fe/day 1088.8 mg/day 387.61 USD/day 1609.9 mg/day 573.12 USD/day
Average iron content per pRBC unit (194.79 mg) 26.15 mg Fe/day 1589.7 mg/day 565.93 USD/day 2350.6 mg/day 836.6 USD/day
Maximum iron content per pRBC unit (276.89 mg) 37.17 mg Fe/day 2259.6 mg/day 804.42 USD/day 3341.1 mg/day 1189.43 USD/day