Table 3.
Modelling of iron load and deferasirox doses and costs based on List et al.[ 45 ]
| Mean transfusion rate: 4.1 pRBC units per month over 12 months (Σ = 49 pRBCs per year) |
Required amount of Deferasirox 20 mg kg−1 bw/d Mean net excretion = 0.329 mg Fe/kg bw/d |
Required amount of Deferasirox 40 mg kg−1 bw/d Mean net excretion = 0.445 mg Fe/kg bw/d |
|||
|---|---|---|---|---|---|
| Minimum iron content per pRBC unit (133.42 mg) | 17.91 mg Fe/day | 1088.8 mg/day | 387.61 USD/day | 1609.9 mg/day | 573.12 USD/day |
| Average iron content per pRBC unit (194.79 mg) | 26.15 mg Fe/day | 1589.7 mg/day | 565.93 USD/day | 2350.6 mg/day | 836.6 USD/day |
| Maximum iron content per pRBC unit (276.89 mg) | 37.17 mg Fe/day | 2259.6 mg/day | 804.42 USD/day | 3341.1 mg/day | 1189.43 USD/day |