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. Author manuscript; available in PMC: 2022 Dec 29.
Published in final edited form as: Cell Rep. 2022 Sep 13;40(11):111334. doi: 10.1016/j.celrep.2022.111334

Figure 4. PI3K p110δ in the MO is necessary for value-based action.

Figure 4.

(A) Schematic of TrkB-PI3K signaling regulating spine structure through Rho kinase (ROCK) and cofilin.

(B) Representative infusion of mCherry-tagged sh-Pik3cd in the MO.

(C) Response acquisition.

(D) Food consumption during CTA.

(E) Reduction of p110δ in the MO impaired value-based action selection. Symbols and shading, means ± SEMs; bars and lines connecting bars, means + individual data points; *p < 0.05. n = 6 control and n = 5 Pik3cd KD.