Table 2.

Key Resources for Evaluating Evidence of Pharmacogenetic Associations

Resource	Key information to be gained by the individual	URL
PharmGKB	• Review annotated literature (e.g., prescribing information, drug label, international pharmacogenetics (pgx) guidelines, clinical and variants)  • Review drug pathway  • Download allele definition, allele functionality, frequency, diplotype-phenotype tables	https://www.pharmgkb.org/
CPIC	• Download CPIC guidelines and supplements  • Obtain key updates on guidelines since publication  • Clinical decision support resources	https://cpicpgx.org/
DPWG	• Download DPWG guidelines  • Read background on enzymes	https://www.knmp.nl/patientenzorg/medicatiebewaking/farmacogenetica/pharmacogenetics-1/pharmacogenetics
Association for Molecular Pathology with College of American Pathologists	• Review published Guidelines on Genotyping Allele Selection for various pharmacogenes	https://www.amp.org/clinical-practice/practice-guidelines/
PharmVar	• Review variants of genes; nomenclature, evidence level, clinical function	https://www.pharmvar.org/

PharmGKB: Pharmagogenomics Knowledege Base; CPIC: Clinical Pharmacogenetics Implementation Consortium; DPWG: Dutch Pharmacogenetics Working Group; PharmVar: Pharmacogene Variation