Table 2.
The diverse cellular applications of various animal lectin families (Vasta et al. 2007)
| Lectin family | Major cellular function |
|---|---|
| C-Type lectin | Cell adhesion (selectin), glycoprotein handling, and clearance mediate innate immunity through various receptor binding. (collectins) |
| S-Type lectin/Galectin | oligosaccharide processing through crosslinking in the extracellular region |
| M-Type lectin | Processing and degradation of glycoprotein in endoplasmic reticulum |
| I-Type lectin | cell adhesion (siglecs) |
| L-Type lectin | protein sorting and selection in endoplasmic reticulum |
| R-Type lectin | lysosomal enzyme targeting, glycoprotein hormone balancing |
| P-Lectin | Targeting lysosomal enzymes, protein sorting in Golgi, Endoplasmic reticulum-mediated degradation of glycoprotein and trafficking |
| Calnexin | protein sorting in ER |
| F-Lectin | innate immunity |
| Intelectin | Innate immunity, embryogenesis |
| Chitinase-like lectin | collagen metabolism |
| F-box lectin | Degradation of misfolded glycoproteins |