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. 2022 Dec 29;12:22570. doi: 10.1038/s41598-022-26943-z

Table 2.

Demographic and clinical characteristics of participant’s patients.

Control Moderate Severe P value
N (%) 11 (29.7) 12 (32.4) 14 (37.8)
Age in year, mean (range) 38.2 (28–78) 45.1 (21–69) 57.6 (28–88) P < 0.04
Male, n (%) 6(54.4) 7(58.3) 9(64.2)
Female, n (%) 5(45.4) 5(41.6) 5(35.7)
Comorbidities
Autoimmune diseases, n (%) 0 (0) 1 (8.3) 5 (35.7) P = 0.03
Cancer, n (%) 0 (0) 0 (0) 2 (14.2) P = 0.03
Infection, n (%) 0 (0) 0 (0) 8 (57.1) P = 0.02
Laboratory analyses
WBC, Mean (109 cell/L) 7.01 7.20 11.62 P = 0.08
Neutrophils, Mean (109 cell/L) 4.01 5.10 10.03 P = 0.002
Monocytes, Mean (109 cell/L) 0.4 0.7 0.8 P = 0.01
Lymphocytes, Mean (109 cell/L) 2.01 1.6 0.93 P = 0.001
O2 Saturation, mean (range) 98 (97–98) 91.41 (87–94) 18.82 (16.3–28) P = 0.001
Ct value, mean (range) 35.10 (33.6–40) 22.17 (18.51–28.43) 20.97 (17.41–28.43) P = 0.01

*Lymphocyte count, Ct value; WBC and neutrophil, counts at the time point of the lowest lymphocyte count. Normal range: WBC 3.5 × 109/L to 8.8 × 109/L, lymphocytes 1.1 × 109/L to 3.5 × 109/L, neutrophils 1.6 × 109/L to 5.9 × 109/L.