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Jejunal biopsies from normal volunteers with experimental human cryptosporidiosis were probed by in situ hybridization using [35S]-labeled riboprobes for cytokine mRNA. Cytokine mRNA is detected as numerous black-silver grains overlying cells primarily in the lamina propria of the villi (arrowhead) and crypts (arrows). The original magnification of both photographs was 500×. (A) TNF-α. (B) IL-1β.
