Table 1. The p54 interactome includes 22 among 40 proteins described as paraspeckle components.
The paraspeckle components listed in the reports by Naganuma et al., 2012 and by Yamamoto et al., 2021 is presented here with their ITAF function and their presence in the p54nrb interactome. Their belonging to class I, II, or III of the paraspeckle proteins is indicated. Class I proteins are essential for paraspeckle formation.
| Name | Alternative name | Class | ITAF | Presence in p54nrb MS-IP |
|---|---|---|---|---|
| ASXL1 | MDS/BOPS | I | No | No |
| CELF6 | n/d | No | No | |
| CIRBP | IIIB | No | Yes | |
| CPSF6 | IIIA | No | Yes | |
| CPSF7 | II | No | Yes | |
| DAZAP1 | IB | No | Yes | |
| DLX3 | n/d | No | No | |
| EWSR1 | No | Yes | ||
| FAM113A | II | No | No | |
| FAM98A | II | No | Yes | |
| FIGN | II | No | No | |
| FUS | IB | Yes | Yes | |
| FUSPI1 | SRSF10 | II | No | Yes |
| hnRNPA1 | II | Yes | Yes | |
| hnRNPA1L2 | n/d | No | No | |
| hnRNPF | n/d | No | Yes | |
| hnRNPH1 | n/d | No | Yes | |
| hnRNPH3 | IB | No | No | |
| hnRNPK | IA | Yes | Yes | |
| hnRNPM | n/d | Yes | Yes | |
| hnRNPR | II | Yes | No | |
| hnRNPUL1 | II | No | Yes | |
| MEX3C | n/d | No | No | |
| NUDT21 | IIIA | No | Yes | |
| p54nrb | NONO | IA | Yes | Yes |
| PSPC1 | IIIB | No | Yes | |
| RBM12 | II | No | No | |
| RBM14 | IA | No | No | |
| RBM3 | IIIB | No | Yes | |
| RBM4B | IIIB | No | No | |
| RBM7 | IIIB | No | No | |
| RBMX | IIIB | No | Yes | |
| RUNX3 | IIIB | No | No | |
| SFPQ | PSF | IA | Yes | Yes |
| SS18L1 | n/d | No | No | |
| SWI/SNF | IB | No | No | |
| TAF15 | No | No | ||
| TDP-43 | II | No | No | |
| UBAP2L | IIIA | No | Yes | |
| ZNF335 | TARDBP | IIIB | No | Yes |