Table 3.
SNPs achieving suggestive significance (p < 10–6) for tinnitus.
| rsID | Chr:pos | Gene | A1/A2 | Reference allele | β | A2 freq | p-value |
|---|---|---|---|---|---|---|---|
| rs71595470 | 4: 176,310,931 | GPM6A*, ADAM29* | AATAG/A | AATAG | 0.067 | 0.035 | 2.42E−8 |
| rs138348879 | 10: 30,800,837 | HNRNPA1P32+/MAP3K8* | T/C | T | 0.085 | 0.02 | 1.24E−7 |
| rs72815660 | 10: 106,614,698 | SORCS3** | A/G | A | 0.06 | 0.039 | 1.89E−7 |
| rs115280365 | 14: 62,444,770 | SYT16** | C/T | C | − 0.06 | 0.039 | 1.90E−7 |
| rs2977458 | 8: 141,576,720 | AGO2** | G/T | G | − 0.25 | 0.301 | 2.76E−7 |
| rs11174486 | 12: 62,848,152 | MON2* | G/A | G | 0.024 | 0.36 | 3.08E−7 |
| rs6830642 | 4: 80,812,744 | ANTXR2* | T/C | T | 0.033 | 0.86 | 3.31E−7 |
| 16: 13,029,711 | SHISA9** | G/GA | G | − 0.026 | 0.705 | 3.77E−7 | |
| 22: 40,560,229 | TNRC6B** | GA/G | GA | 0.023 | 0.605 | 4.06E−7 | |
| rs10225195 | 7: 109,167,243 | DNAJB9* | T/C | T | 0.022 | 0.476 | 4.54E−7 |
| rs112291465 | 15: 25,874,698 | ATP10A* | T/A | T | 0.033 | 0.139 | 4.88E−7 |
| rs9841474 | 3: 55,206,208 | CACNAD3* | G/A | G | 0.027 | 0.217 | 5.18E−7 |
| rs145362852 | 18: 2,600,477 | NDC80* | G/A | G | 0.069 | 0.028 | 5.25E−7 |
| rs145529681 | 2: 60,073,205 | BCL11A* | C/G | C | 0.067 | 0.029 | 6.37E−7 |
| rs201893107 | 14: 72,429,274 | RGS6** | CTG/C | CTG | 0.117 | 0.01 | 6.92E−7 |
| 8: 69,546,107 | C8orf34** | GT/G | GT | − 0.023 | 0.647 | 7.42E−7 | |
| rs12155428 | 7: 3,425,301 | SDK1** | C/T | C | 0.061 | 0.033 | 7.72E−7 |
| rs11164650 | 1: 103,448,242 | COL11A1** | T/G | T | − 0.025 | 0.248 | 9.20E−7 |
| rs727415 | 10: 73,582,752 | PSAP** | T/A | T | 0.024 | 0.293 | 9.77E−7 |
| rs79604213 | 13: 93,040,866 | GPC5** | A/G | A | 0.116 | 0.009 | 9.98E−7 |
Significant values are in bold.
**Within a gene body.
*Nearest gene.
+Pseudogene.