Table 5.
SNP rsID | Chr:pos | A1 | A2 | Current study | Clifford et al.23 | Wells et al.24 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
β | A1 Freq | p-value | β | A1 Freq | p-value | β | A1 Freq | p-value | ||||
rs143424888 | 1:103,456,996 | C | CACGTGATCT | − 0.021 | 0.508 | 2.8E−6 | − 0.023 | 0.510 | 8.5E−9 | − 0.006 | 0.508 | 9.0E−6 |
rs17249745 | 4:102,547,366 | A | G | − 0.049 | 0.967 | 2.3E−4 | − 0.072 | 0.967 | 1.3E−9 | − 0.018 | 0.968 | 1.0E−5 |
rs553448379 | 6:43,288,656 | T | TA | − 0.022 | 0.385 | 1.6E−6 | − 0.023 | 0.386 | 2.1E−8 | − 0.007 | 0.384 | 4.6E−7 |
rs11249981 | 8:10,147,398 | C | T | − 0.018 | 0.448 | 6.2E−5 | − 0.022 | 0.447 | 4.6E−8 | − 0.007 | 0.449 | 1.2E−6 |
rs72815660 | 10:106,614,698 | A | G | − 0.060 | 0.961 | 1.8E−7 | − 0.060 | 0.960 | 9.7E−9 | − 0.014 | 0.961 | 4.1E−5 |
rs11174489 | 12:62,852,271 | G | A | − 0.023 | 0.625 | 5.4E−7 | − 0.024 | 0.625 | 3.8E−9 | − 0.006 | 0.626 | 1.1E−5 |
Significant values are in bold.
rs143424888, rs553448379, and rs11249981 were replicated in the Million Veteran Program sample by Clifford et al.23. SNP rsID presents the rsID of the single nucleotide polymorphism (SNP). Chr:por presents the chromosomal number and position of SNP, A1 is the frequency is of A1 allele, and A2 is the frequency of A2 allele, beta presents the regression correlation coefficient, and p-value presents the observed p-value of the regression coefficient.