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. 2022 Dec 29;13:7975. doi: 10.1038/s41467-022-35743-y

Fig. 5. ROC curve analysis.

Fig. 5

a–e ROC curves for GUIDE-seq (red), nDigenome-seq (orange), and TAPE-seq using PE2 (green), PE2-nuclease (blue), and PEmax-nuclease with epegRNAs (purple) for the a HEK4 (+2 G to T), b HEK4 (+3 TAA ins), c HBB (+4 A to T), d DNMT1 (+6 G to C), and e HEK3 (+1 CTT ins) pegRNAs. f Area under ROC curves (n = 6 independent experiments for GUIDE-seq and n = 10 independent experiments for the rest of the methods each represented by different color). The bars represent the mean. Error bars indicate standard deviation.