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. 2022 Dec 16;13:1081553. doi: 10.3389/fphar.2022.1081553

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Copyright © 2022 Li, Zhuge, Wang, Xia, Wang, Han, Shen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The combination of OCA and Fer-1 differentially reshaped intestinal microbiome. (A) LEfSe cladogram represents the taxa enriched in the AMLN diet group and the OCA + Fer-1 group. (B) Taxa with significant differences between the AMLN diet group and the OCA + Fer-1 group. (C) LEfSe cladogram represents the taxa enriched in the OCA group and the OCA + Fer-1 group. (D) Taxa with significant differences between the OCA group and the OCA + Fer-1 group. Data are shown as mean ± SEM.