Table 1.

The details surrounding the patient’s treatment: HGG, high-grade glioma; STR, subtotal resection; GTR, gross-total resection.

	Tumor localization	Number and extent of surgical treatments for HGG (time relapse)	Histological examination	Infectious complication/number of surgical treatments for infectious complications (etiology/antibiotic resistance)	ATB treatment (duration)	Outcome
Case 1	Left parietal lobe	1. HGG resection (STR) 2. HGG resection after 5 months (GTR)	Glioblastoma WHO G IV, IDH-wildtype, MGMT promoter hypermethylation	Osteomyelitis/4 Staphylococcus aureus/resistance to clindamycin and erythromycin	Biseptol (680 days) Cefuroxime (60 days) Linezolid (21 days) Ospamo (23 days)	disease-free survival of 61 months
Case 2	Left frontal lobe	1. HGG resection (GTR) 2. HGG resection after 6 years (GTR)	Anaplastic astrocytoma, WHO GIII, IDH-mutant	Osteomyelitis/2 Staphylococcus aureus/not resistant Pseudomonas aeruginosa/resistant to piperacillin+tazobactam and ciprofloxacin Klebsiella pneumoniae/resistant to chloramphenicol and Biseptol)	Biseptol (60 days) Ceftazidime (14 days)	disease-free survival of 152 months