Figure 2.
Dual-modified RBC membrane-camouflaged solid lipid NPs (T7/NGR-RBCSLNs) for enhanced glioma targeting. (A) Schematic illustration of the preparation procedure of T7/NGR-RBCSLNs. Penetrating efficiency of the indicated NPs in the in vitro models of the (B) blood-brain barrier (BBB) and (C) blood-brain tumor barrier (BBTB). (D) Biodistribution of the indicated Cy5.5-loaded NPs in glioma-bearing mice. Adapted with permission from 75, copyright 2018, American Chemical Society.