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. 2022 Dec 30;160(8):347–351. doi: 10.1016/j.medcli.2022.11.018

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Fig. 2 — Proposed invasion pathways for SARS-CoV-2 in the olfactory epithelium. Abbreviation: SC: stem cell; SuC: sustentacular cell; iORN: immature olfactory receptor; mORN: mature olfactory receptor. Pathway 1: The virus invades sustentacular cells via ACE2 receptors. Pathway 2: the virus reaches the olfactory receptors from the sustentacular cells through exosomes. Pathway 3: the virus invades stem cells before they differentiate into olfactory receptor.