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. 2022 Dec 16;10:980548. doi: 10.3389/fbioe.2022.980548

TABLE 3.

The application of exosomes and EVs in stroke clinical trials.

ClinicalTrials.gov identifier Official tittle Study type First posted Estimated/Actual study start date Condition or disease Intervention/Treatement
NCT05326724 The Role of Acupuncture-induced Exosome in Treating Post-stroke Dementia Interventional (clinical trial) 13 April 2022 1 August 2022 Exosome Device: Acupuncture
Post-stroke Dementia
Acupuncture
NCT03384433 Allogenic Mesenchymal Stem Cell Derived Exosome in Patients with Acute Ischemic Stroke Interventional (clinical trial) 27 December 2017 17 April 2019 Cerebrovascular disorders Biological: exosome
NCT05370105 Extracellular Vesicles as Stroke Biomarkers (EXO4STROKE) Observational 11 May 2022 25 June 2018 Stroke Rehabilitation Other: blood withdrawal
NCT05524506 PROgnostic Value of MicroParticles and Markers of Hemostasis in TIA and Ischemic Stroke (PROMPTS) Observational 1 September 2022 June 2007 Brain Ischemia -
Cerebral Ischemia
Extracellular Vesicles
Hemostasis
Prognosis