Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 16;9:1080964. doi: 10.3389/fmolb.2022.1080964

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Fredericks, East, Shi, Liu, Maschietto, Ayala, Cioffi, Cohen, Fairbrother, Lefort, Nau, Levy, Wang, Batista, Lisi and Monaghan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Comparison of MD-derived conformation A (blue) and B (magenta) with the starting conformation S (multicolor). (A) Starting conformation S. (B) Superposition between conformations S and (A). (C) Superposition between conformations S and (B). (D) Two orthogonal views of conformations S, A and (B). (E) Conformation S in context of the spike trimer with NTD and RBD of neighboring subunits included. (F) Superposition of conformations S and A in the context of the spike protein. (G) Superposition of conformations S and B in the trimer. (H) Compiled view of conformation S and A/B in the trimer.