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. 2022 Dec 16;12:973045. doi: 10.3389/fonc.2022.973045

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Copyright © 2022 Guo, Zhang and Kong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A 41-year-old female patient who was diagnosed with hepatitis B more than 10 years ago underwent CT examination due to epigastric pain, and CT findings indicated a large hepatocellular carcinoma in the right lobe of the liver (A). The patient underwent two DEB-TACE treatment sessions. After 6 weeks, CT reexamination revealed a significant reduction in necrosis of the liver tumor; however, multiple intrahepatic bile duct necroses were observed around the tumor without significant enhancement (B–D) (red arrow).