Table 4.

Results of CSNI and CSNS treatments for patients with CRSwNP.

Patients with CRSwNP		Treatment cycle						Test	p-value
		CSNI		CSNS		Total
		n = 243		n = 246		n = 489
Time of treatment (days)	M/SD	154.5	102.2	149.6	72.7	152.0	88.5	T	0.54
Subjective improvement	n (%)	205	84.4	193	78.5	398	81.4	Chi	0.09
Pre-treatment SNOT-22	M/SD	31.6	23.6	27.7	22.4	29.6	23.1	T	0.06
Post-treatment SNOT-22	M/SD	30.0	24.9	26.6	23.2	28.3	24.1	T	0.12
		Pre-post T	0.09	Pre-post T	0.17	Pre-post T	0.05a
Pre-treatment total LKES	M/SD	5.1	3.0	4.9	3.3	5.0	3.2	T	0.42
Post-treatment total LKES	M/SD	4.8	3.2	4.6	3.2	4.7	3.2	T	0.44
		Pre-post T	0.04a	Pre-post T	0.03a	Pre-post T	0.005a
Adverse events	n (%)	6	2.5	1	0.4	8	1.6	Fisher	0.07
Exacerbations	n (%)	15	6.2	26	10.6	41	8.4	Chi	0.08
Need for subsequent surgery	n (%)	28	11.5	30	12.2	58	11.9	Chi	0.82

Chi, Chi-square test; CSNI, corticosteroid nasal irrigation; CSNS, Topical corticosteroid nasal spray; Fisher, Fisher exact test; M, mean; SD, standard deviation; n, number; %, percentage; LKES, Lund–Kennedy endoscopic score; SNOT-22 (BR), SinoNasal Outcome Test-22 in Brazilian Portuguese; T, T-test.

^ap < 0.05.