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. 2021 Aug 4;88(Suppl 5):S32–S41. doi: 10.1016/j.bjorl.2021.06.008

Table 7.

Result of CSNI treatments with 1% compounded budesonide drops and betamethasone cream.

Types of CSNI Treatment cycle
Test p-Value
1% Budesonide
Betamethasone
Total
n = 149 n = 143 n = 292
Treatment time (days) M/SD 158.4 111.8 142.7 81.1 150.7 98.4 T 0.17
Subjective improvement n (%) 123 82.6 118 82.5 241 82.5 Chi 1.00
Pre-treatment SNOT-22 M/SD 31.8 22.3 33.9 25.1 32.8 23.8 T 0.45
Post-treatment SNOT-22 M/SD 29.6 22.7 32.8 26.8 31.2 24.9 T 0.26
Pre-post T 0.09 Pre-post T 0.21 Pre-post T 0.06
Pre-treatment total LKES M/SD 5.1 3.1 4.4 2.9 4.8 3.0 T 0.04a
Post-treatment total LKES M/SD 4.6 3.2 4.2 3.2 4.4 3.2 T 0.28
Pre-post T 0.02a Pre-post T 0.19 Pre-post T 0.01a
Adverse events n (%) 0 0.0 7 4.9 7 2.4 Fisher 0.006a
Exacerbations n (%) 13 8.7 6 4.2 19 6.5 Fisher 0.12
Need for subsequent surgery n (%) 13 8.7 20 14.0 33 11.3 Chi 0.16

Chi, Chi-square test; CSNI, corticosteroid nasal irrigation; CSNS, Topical corticosteroid nasal spray; Fisher, Fisher exact test; M, mean; SD, standard deviation; n, number; %, percentage; LKES, Lund–Kennedy endoscopic score; SNOT-22 (BR), SinoNasal Outcome Test-22 in Brazilian Portuguese; T, T-test.

a

p < 0.05.