Table 8.
Budesonide doses | Treatment cycle with 1% budesonide |
Test | p-Value | ||||||
---|---|---|---|---|---|---|---|---|---|
1000 µg |
500 µg |
Total |
|||||||
n = 149 | n = 143 | n = 292 | |||||||
Treatment time (days) | M/SD | 161.7 | 136.3 | 162.9 | 837.0 | 162.3 | 114.6 | T | 0.95 |
Subjective improvement | n (%) | 61 | 84.7 | 53 | 80.3 | 114 | 82.6 | Chi | 0.49 |
Pre-treatment SNOT-22 | M/SD | 30.7 | 23.1 | 32.6 | 22.1 | 31.6 | 22.7 | T | 0.63 |
Post-treatment SNOT-22 | M/SD | 27.0 | 23.9 | 32.2 | 22.3 | 29.5 | 23.4 | T | 0.19 |
Pre-post T | 0.06 | Pre-post T | 0.43 | Pre-post T | 0.10 | ||||
Pre-treatment total LKES | M/SD | 5.5 | 2.5 | 4.8 | 3.4 | 5.2 | 3.0 | T | 0.20 |
Post-treatment total LKES | M/SD | 4.8 | 2.9 | 4.3 | 3.4 | 4.6 | 3.2 | T | 0.35 |
Pre-post T | 0.03a | Pre-post T | 0.08 | Pre-post T | 0.009a | ||||
Adverse events | n (%) | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | Fisher | 1.00 |
Exacerbations | n (%) | 5 | 6.9 | 6 | 9.1 | 11 | 8.0 | Chi | 0.64 |
Need for subsequent surgery | n (%) | 5 | 6.9 | 6 | 9.1 | 11 | 8.0 | Chi | 0.64 |
Chi, Chi-square test; CSNI, corticosteroid nasal irrigation; Fisher, Fisher exact test; M, mean; SD, standard deviation; n, number; %, percentage; LKES, Lund–Kennedy endoscopic score; SNOT-22 (BR), SinoNasal Outcome Test-22 in Brazilian Portuguese; T, T-test.
p < 0.05.