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. 2021 Aug 4;88(Suppl 5):S32–S41. doi: 10.1016/j.bjorl.2021.06.008

Table 8.

Result of CSNI doses with 1% compounded budesonide drops.

Budesonide doses Treatment cycle with 1% budesonide
Test p-Value
1000 µg
500 µg
Total
n = 149 n = 143 n = 292
Treatment time (days) M/SD 161.7 136.3 162.9 837.0 162.3 114.6 T 0.95
Subjective improvement n (%) 61 84.7 53 80.3 114 82.6 Chi 0.49
Pre-treatment SNOT-22 M/SD 30.7 23.1 32.6 22.1 31.6 22.7 T 0.63
Post-treatment SNOT-22 M/SD 27.0 23.9 32.2 22.3 29.5 23.4 T 0.19
Pre-post T 0.06 Pre-post T 0.43 Pre-post T 0.10
Pre-treatment total LKES M/SD 5.5 2.5 4.8 3.4 5.2 3.0 T 0.20
Post-treatment total LKES M/SD 4.8 2.9 4.3 3.4 4.6 3.2 T 0.35
Pre-post T 0.03a Pre-post T 0.08 Pre-post T 0.009a
Adverse events n (%) 0 0.0 0 0.0 0 0.0 Fisher 1.00
Exacerbations n (%) 5 6.9 6 9.1 11 8.0 Chi 0.64
Need for subsequent surgery n (%) 5 6.9 6 9.1 11 8.0 Chi 0.64

Chi, Chi-square test; CSNI, corticosteroid nasal irrigation; Fisher, Fisher exact test; M, mean; SD, standard deviation; n, number; %, percentage; LKES, Lund–Kennedy endoscopic score; SNOT-22 (BR), SinoNasal Outcome Test-22 in Brazilian Portuguese; T, T-test.

a

p < 0.05.