Table 1.
Estimates of selective pressure as well as substitution rates in human–mouse orthologs
|
Non-coding |
Coding |
|||||
|---|---|---|---|---|---|---|
| Gene symbol | Kn | ξ = Kn/Ks | Gene symbol | Ka | Ks | ω = Ka/Ks |
| H19 | 0.340 | 0.296 | MRPL23 | 0.088 | 1.150 | 0.077 |
| MALAT1 | 0.324 | 0.464 | SCYL1 | 0.040 | 0.697 | 0.058 |
| HOTAIR | 0.544 | 1.114 | HOXC12 | 0.020 | 0.488 | 0.041 |
Note: Ka, nonsynonymous substitution rate; Ks, synonymous substitution rate; Kn, non-coding nucleotide substitution rate; ω, selective pressure on coding sequence; ξ, selective pressure on non-coding sequence.