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. 2022 Aug 3;12:221–233. doi: 10.1016/j.xjon.2022.07.007

Figure 1.

Figure 1

The protocols of animal modeling. A, Flow chart of animal modeling. The rats were randomly allocated to 3 groups: Sham (n = 15), ECPR (n = 20), and CP-ECPR (n = 20) groups. B, Schematic diagram of SHCP approach in the ECPR rats. The tube for cerebral perfusion, covered with a cooling bag, was connected to the ECMO circuits. The brain temperature selectively decreased to 26 to 28 °C in the CP-ECPR rats. MAP, Mean arterial pressure; ECPR, extracorporeal cardiopulmonary resuscitation; CP-ECPR, SHCP combined ECPR; SHCP, selective hypothermic cerebral perfusion; ECMO, extracorporeal membrane oxygenation; BP, blood pressure.