Table 3. The frequencies of common genetic polymorphisms causing thrombophilia.

	Group 1 (n=52)		Group 2 (n=52)		Group 3 (n=51)			P value for pairwise comparison
	n	%	n	%	n	%	p	(I→II)	(I→III)	(II→III)
MTHFR A1298C
Normal	19	36.5	19	36.5	29I,II	56.9		NS	0.039	0.039
Heterozygote	22	42.3	28	53.8	18	35.3	0.048†	NS	NS	NS
Homozygote	11	21.2	5	9.6	4	7.8		NS	NS	NS
MTHFR C677T
Normal	25	48.1	23	44.2	27	52.9		NS	NS	NS
Heterozygote	24	46.2	21	40.4	17	33.3	0.441†	NS	NS	NS
Homozygote	3	5.8	8	15.4	7	13.7		NS	NS	NS
Compound heterozygote	16	30.8	15	28.8	6	11.8	0.048†	NS	0.019	0.031
MTHFR
Factor II (G2021A)
Normal	48	92.3	48	92.3	49	96.1		NS	NS	NS
Heterozygote	4	7.7	4	7.7	2	3.9	0.772‡	NS	NS	NS
Homozygote	0	0.0	0	0.0	0	0.0		NS	NS	NS
Factor V (Leiden)
Normal	47	90.4	47	90.4	47	92.2		NS	NS	NS
Heterozygote	3	5.8	5	9.6	4	7.8	0.576‡	NS	NS	NS
Homozygote	2	3.8	0	0.0	0	0.0		NS	NS	NS
PAI
4G/4G	8	15.4	8	15.4	14	27.5		NS	NS	NS
4G/5G	33	63.5	32	61.5	28	54.9	0.528†	NS	NS	NS
5G/5G	11	21.2	12	23.1	9	17.6		NS	NS	NS
Factor XIII (V34L)
Normal	34	65.4	30	57.7	39	76.5		NS	NS	NS
Heterozygote	16	30.8	22	42.3	11	21.6	0.106‡	NS	NS	NS
Homozygote	2	3.8	0	0.0	1	2.0		NS	NS	NS
MTHFR: Methylene tetrahydrofolate reductase; PAI: Plasminogen activator inhibitor; NS: Not significant; † Pearson chi-square test, ‡ Fisher Freeman Halton. test