Fig. 4.

The differential expression analysis of baseline tumour samples. a Differential expression between the response group and the non-response group in baseline tumour samples. b CHI3L1 expression in baseline tumour samples showed a better predictive ability to treatment response than PD-L1. c The difference in OS between high and low CHI3L1 IHC scores in baseline tumour samples. d The difference in PFS between high and low CHI3L1 IHC scores in baseline tumour samples. e CHI3L1 IHC expression comparison in baseline tumour samples between non-response and response groups. f Representative IHC images for CHI3L1 in different response groups