Table 3.
Reasons That the Patients Were Not in Remission and/or Stopped the Drug
| Primary Outcome Reason | Single Switch | Double Switch | Total | |||
|---|---|---|---|---|---|---|
| N | % | N | % | N | % | |
| Discontinued SB2 within 1 year | 13 | 12.9 | 30 | 17.6 | 43 | 15.9 |
| Loss of response | 9 | 8.9 | 15 | 8.8 | 24 | 8.9 |
| Hypersensitivity reaction | 2 | 2.0 | 6 | 3.5 | 8 | 3.0 |
| Refused treatment | 0 | 0.0 | 3 | 1.8 | 3 | 1.1 |
| Secondary to infection | 0 | 0.0 | 2 | 1.2 | 2 | 0.7 |
| Secondary to malignancy | 1 | 1.0 | 3 | 1.8 | 4 | 1.5 |
| Other | 1 | 1.0 | 1 | 0.6 | 2 | 0.7 |
| Continued SB2, not in remission after 1 year | 12 | 11.9 | 16 | 9.4 | 28 | 10.3 |
| Required dosage increase | 8 | 7.9 | 9 | 5.3 | 17 | 6.3 |
| Steroids utilization | 3 | 3.0 | 4 | 2.4 | 7 | 2.6 |
| Hospitalized for IBD | 1 | 1.0 | 3 | 1.8 | 4 | 1.5 |