Table 1.
Methylation and expression differences of steroidogenic genes between TTFs and LCs.
| Gene name | MethDif a (P_value) | DMR (distance to TSS) | Fold change of mRNAb (P_value) |
|---|---|---|---|
| Nr5a1 | −0.524 (1.61E-46) | Promoter (<1 kb) | 8.533 (1.40E-76) |
| Lhcgr | −0.299 (7.97E-46) | Distal intergenic (−185 kb) | 3.515 (6.21E-115) |
| Hsd17b3 | −0.289 (4.45E-08) | Promoter (<1 kb) | 7.814 (4.20E-09) |
| Scarb1 | −0.258 (7.22E-31) | Distal intergenic (68 kb) | 1.601 (7.15E-17) |
| Nr5a2 | 0.216 (2.65E-34) | Distal intergenic (−427 kb) | −3.639 (1.60E-10) |
| Nr1h3 | 0.267 (5.43E-16) | Promoter (1–2 kb) | −1.934 (4.60E-05) |
a
The value of methDif was presented by the different levels of DMR (TTFs versus LCs).
b
The value of expression fold change was presented as log2 format.