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. 2022 Dec 16;13:1034818. doi: 10.3389/fendo.2022.1034818

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Copyright © 2022 Wang, Guo, Bai, Cui, Zhang, Li, Shang and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of general, laboratory and pathological indexes. (A, B) Line graphs of mouse RBG and T/Cr at different time points. (C) Scatter plot of ratio of right kidney weight/body weight. (D) Scatter plot of plasma creatinine. (E) HE/Masson/PAS staining of mouse kidney tissue in each group. (F) IHC staining of nephrin, vimentin, collagen IV, fibronectin expression in kidney tissue. (G) Expression levels of vimentin, collagen IV, α-SMA in kidney tissue by Western blot analysis. *: DKD VS Con, ^#: En VS Con and En VS DKD. * and ^# p < 0.05, ** and ^## p < 0.01, ***p < 0.001, **** and ^#### p < 0.0001.