Table 3.

Estimated Means and Associated 95% CIs, by Treatment Group and Time Point, for Primary and Secondary Continuous Outcomes

Outcome	Estimated Mean (95% CI)*
	Baseline	3-Month Follow-up	6-Month Follow-up	9-Month Follow-up	12-Month Follow-up
PEGS score (0–10)
Usual care	6.645 (6.447–6.843)	6.210 (5.994–6.426)	6.197 (5.994–6.399)	6.183 (5.976–6.390)	6.170 (5.940–6.400)
CBT	6.485 (6.290–6.681)	5.486 (5.272–5.699)	5.516 (5.316–5.715)	5.546 (5.342–5.750)	5.576 (5.349–5.803)
PEG score (0–10)
Usual care	6.750 (6.550–6.950)	6.295 (6.077–6.514)	6.277 (6.074–6.481)	6.259 (6.051–6.468)	6.242 (6.010–6.473)
CBT	6.643 (6.446–6.840)	5.581 (5.365–5.796)	5.621 (5.420–5.821)	5.660 (5.455–5.866)	5.700 (5.472–5.929)
RMDQ score (0–1)
Usual care	0.692 (0.672–0.711)	0.675 (0.654–0.696)	0.678 (0.658–0.698)	0.681 (0.660–0.701)	0.683 (0.661–0.706)
CBT	0.672 (0.652–0.691)	0.612 (0.591 –0.633)	0.609 (0.590–0.629)	0.607 (0.586–0.627)	0.604 (0.581–0.626)
Satisfaction with primary care services (0–10)
Usual care	4.237 (4.134–4.339)	-	3.984 (3.856–4.112)	-	-
CBT	4.263 (4.162–4.365)	-	4.240 (4.115–4.365)	-	-
Satisfaction with pain services (0–10)
Usual care	3.581 (3.461 –3.700)	-	3.667 (3.538–3.796)	-	-
CBT	3.658 (3.540–3.776)	-	4.080 (3.954–4.205)	-	-
Average daily dose of opioids, MME †
Usual care	55.252 (48.333–62.171)	56.695 (49.556–63.834)	55.563 (48.421–62.704)	54.430 (47.142–61.719)	53.298 (45.725–60.871)
CBT	47.458 (40.647–54.269)	46.641 (39.610–53.627)	45.606 (38.574–52.638)	44.571 (37.396–51.745)	43.536 (36.085–50.986)

MME = morphine milligram equivalents; PEG = pain intensity and interference with enjoyment of life and general activity; PEGS = pain intensity and interference with enjoyment of life, general activity, and sleep; RMDQ = Roland Morris Disability Questionnaire.

^*Based on 3-level, piecewise linear mixed model.

^†Winsorized.