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. 2021 Oct 7;3(4):otab071. doi: 10.1093/crocol/otab071

Table 2.

Results of waste analysis for both the real-world analysis (N = 1003 administrations of infliximab) and the ideal, weight-based analysis (N = 413 IBD patients’ presenting weights).

Real-world analysis (N = 1003) Ideal, weight-based analysis (N = 413)
Infliximab vial size 100 mga 50 mgb 25 mgb 100 mga 50 mgb 25 mgb
Quantity of drug waste per administration, mean ± SD 17.3mg ± 24.6 1.4mg ± 5.8 0.1mg ± 1.4 49.5mg ± 28.2 24.6mg ± 14.3 12.2mg ± 6.8
Financial value of drug waste per administration, mean ± SD Medicare Part B Average Sales Price25 $112.40 ± $159.76 $8.78 ± $37.59 $0.68 ± $8.86 $321.50 ± $183.01 $159.50 ± $92.73 $79.28 ± $44.46
Average Wholesale Price26 $242.48 ± $344.66 $18.93 ± $81.08 $1.47 ± $19.11 $693.58 ± $394.81 $344.08 ± $200.04 $171.03 ± $95.91
Potential waste reduction from current 100mg vials (%) x 92.2% 99.4% x 50.4% 75.3%

Currently manufactured vial size

Theoretical vial sizes.