Table 2.
Results of waste analysis for both the real-world analysis (N = 1003 administrations of infliximab) and the ideal, weight-based analysis (N = 413 IBD patients’ presenting weights).
Real-world analysis (N = 1003) | Ideal, weight-based analysis (N = 413) | ||||||
---|---|---|---|---|---|---|---|
Infliximab vial size | 100 mga | 50 mgb | 25 mgb | 100 mga | 50 mgb | 25 mgb | |
Quantity of drug waste per administration, mean ± SD | 17.3mg ± 24.6 | 1.4mg ± 5.8 | 0.1mg ± 1.4 | 49.5mg ± 28.2 | 24.6mg ± 14.3 | 12.2mg ± 6.8 | |
Financial value of drug waste per administration, mean ± SD | Medicare Part B Average Sales Price25 | $112.40 ± $159.76 | $8.78 ± $37.59 | $0.68 ± $8.86 | $321.50 ± $183.01 | $159.50 ± $92.73 | $79.28 ± $44.46 |
Average Wholesale Price26 | $242.48 ± $344.66 | $18.93 ± $81.08 | $1.47 ± $19.11 | $693.58 ± $394.81 | $344.08 ± $200.04 | $171.03 ± $95.91 | |
Potential waste reduction from current 100mg vials (%) | x | 92.2% | 99.4% | x | 50.4% | 75.3% |
Currently manufactured vial size
Theoretical vial sizes.