TABLE 5.
Mild and Tolerable Side Effects | Severe or Intolerable Side Effects | ||||
---|---|---|---|---|---|
Current Users | Previous Users | Current Users | Previous Users | P* | |
Increased appetite | 62 (68%) | 40 (70%) | 7 (8%) | 0 (0%) | 0.54 |
Dry mouth | 59 (64%) | 31 (54%) | 4 (4%) | 1 (2%) | 0.13 |
Drowsiness or sedation | 50 (55%) | 33 (58%) | 3 (3%) | 1 (2%) | 0.87 |
Memory impairment | 30 (33%) | 17 (30%) | 1 (1%) | 2 (4%) | >0.99 |
Lack of energy or fatigue | 26 (29%) | 20 (35%) | 5 (5%) | 0 (0%) | 0.90 |
Dehydration | 19 (21%) | 10 (18%) | 2 (2%) | 0 (0%) | 0.54 |
Confusion | 18 (20%) | 9 (16%) | 1 (1%) | 0 (0%) | 0.52 |
Dizziness | 16 (17%) | 9 (16%) | 0 (0%) | 0 (0%) | >0.99 |
Bad taste in mouth | 15 (16%) | 12 (21%) | 2 (2%) | 3 (5%) | 0.30 |
Diarrhea | 14 (15%) | 8 (14%) | 2 (2%) | 0 (0%) | 0.83 |
Anxiety | 14 (15%) | 17 (30%) | 1 (1%) | 1 (2%) | 0.042 |
Eye irritation | 13 (14%) | 6 (11%) | 0 (0%) | 1 (2%) | 0.81 |
Respiratory complaints | 9 (10%) | 3 (5%) | 0 (0%) | 3 (5%) | >0.99 |
Racing heart/palpitations | 9 (10%) | 5 (9%) | 0 (0%) | 2 (4%) | 0.79 |
Paranoia | 9 (10%) | 9 (16%) | 0 (0%) | 2 (4%) | 0.14 |
Gastrointestinal irritation | 9 (10%) | 5 (9%) | 0 (0%) | 0 (0%) | >0.99 |
Depressed mood | 9 (10%) | 6 (11%) | 1 (1%) | 0 (0%) | >0.99 |
Nausea/vomiting | 8 (9%) | 3 (5%) | 2 (2%) | 0 (0%) | 0.37 |
Sleep disturbance | 7 (8%) | 4 (7%) | 2 (2%) | 1 (2%) | >0.99 |
Constipation | 6 (7%) | 3 (5%) | 1 (1%) | 0 (0%) | 0.74 |
Sweating | 5 (5%) | 3 (5%) | 1 (1%) | 1 (2%) | >0.99 |
Headaches | 5 (5%) | 5 (9%) | 2 (2%) | 0 (0%) | 0.77 |
Allergies | 4 (4%) | 1 (2%) | 0 (0%) | 0 (0%) | 0.65 |
Shaking/tremor/poor movement control | 3 (3%) | 3 (5%) | 0 (0%) | 1 (2%) | 0.43 |
Decreased appetite | 3 (3%) | 2 (4%) | 1 (1%) | 0 (0%) | >0.99 |
Panic attack | 2 (2%) | 1 (2%) | 0 (0%) | 1 (2%) | 0.64 |
Nasopharyngeal complaints | 2 (2%) | 3 (5%) | 1 (1%) | 0 (0%) | 0.68 |
Cannabis hyperemesis | 2 (2%) | 2 (4%) | 1 (1%) | 0 (0%) | >0.99 |
Hallucinations | 1 (1%) | 4 (7%) | 0 (0%) | 0 (0%) | 0.072 |
Delusions | 0 (0%) | 6 (11%) | 1 (1%) | 0 (0%) | 0.014 |
Number of respondents; current users = 89–92; previous users = 56–57.
*P value represents contingency test between current and previous users of all side effects experienced (severe and mild combined) using a χ 2 analysis or Fisher’s exact test where n < 20.