Fig. 3.

Choroidal thickness and axial length development in C57B6/J mice. (A) Representative H&E-stained cross-sections of enucleated eyes from wild-type C57B6/J mice and (B) measurement of choroidal thickness according to its distance from the optic nerve. Thickness of choroid is relatively thicker in the posterior pole than the anterior pole n = 3. (C) Choroidal thickness measurement by OCT images shows that choroidal thickness gradually increases and reaches a plateau at about 7 to 9 weeks old after then the thickness gradually become thinner along with the age n = 3. (D) Axial length, (E) refraction error, and (F) vitreous chamber depth with growth showing axial length increase with age and emmetropic refractive status. Numbers between each time point in D indicate slope n = 6. Graphs represent as mean ± SD.